Oatext Integrative Cancer Science Journal and Therapeutics (ICST) is an open access, peer-reviewed online journal interested in attracting high-quality original research and reviews that present or highlight significant advances in all areas of cancer and related biomedical science.
Standard oligonucleotide-directed site-specific mutagenesis methods can produce well-defined sequence changes, but the creation of large numbers of mutants can be both time- and cost-prohibitive. In contrast, the mutagenesis oligo libraries that can be created give you precise, codon-level control over the variants that are produced.
In vitro molecular optimization is a very efficient means of generating mutant proteins with improved or novel properties, identifying regulatory sequences, and probing for structurally and functionally critical residues.
DPI measures the structure of a protein in one dimension (i.e. Its diameter or size) and the density (i.e. Its mass per unit volume or how tightly folded it is) by coupling the protein to a glass slide and probing its structure using non-diffractive optics.
DSC technique is very convenient requiring only minimal assay development, NO labeling or immobilization, and permits screening of large numbers of samples at low concentrations minimizing the consumption of valuable samples. It does this by measuring the heat change associated with the molecule's thermal denaturation when heated at a constant rate.
In biology, particularly in studies relating the structure of macromolecules to their functions, two of the most important questions are (i) how tightly does a small molecule bind to a specific interaction site and (ii) how fast does the reaction take place if the molecule is a substrate and is converted to a product? ITC is a quantitative technique that can determine the...
Mutagenesis is a fundamentally important DNA manipulation technique. It involves changing the base sequence of the DNA molecule, usually for the purposes of testing the effect of this change on gene or DNA function. Most site-directed mutagenesis is based on the PCR method.
In 95% of T cells, this consists of an α and β chain, whereas in 5% of T cells this consists of γ and δ chains. This ratio changes during ontogeny and in diseased states. So the idiotype of each V region of a single immunoglobulin molecule may be comprised of as many as 15-20 idiotopes, which can be distinguished by monoclonal anti-idiotypic antibodies or...
Manufacturability assessment consists of both productivity and stability assessment. Productivity is evaluated by which the product is manufactured with the correct structure and post-translational modifications at desired levels from a production cell line, purified in an intact form.
All important topic of biology subject is explain in Revision Notes For Class 12 Biology. Take the help of this visit for reduce student complexity Scholarslearning provides best study notes revision notes and mores study stuff. Here also student can do online study.
The fluorescence microscopy developed to one of the most important tools of the life science area. The observation of the fluorescence emergencies in biological samples delivers differentiates conclusions about morphology and functionality of cells. The objects of examination reach from fixated cells via chromosomes and genes up to observation of processes in living cells.
Vinnbio products are manufactured in the Unites States of America under strict quality control standards and sold as dry powders with more than two years of shelf life. Our products are quick to activate in pond water and ready to use in less than an hour due to their superior quality.
Creative Biogene is offering a comprehensive screen of cellular and biochemical nuclear receptor assays to profile your compounds. Measurements of ligand binding activity, NRs translocation and NR-coregulator interaction are included to characterize the selectivity and potential off-target events. With our extraordinary experience in drug discovery programs, we are able to...
As one of the most important post-translational modifications of proteins in eukaryotic cells, protein glycosylation is involved in a wide range of biological and physiological processes, including recognition & regulatory functions, cellular communication, gene expression, cellular immunity, growth and development.
As a leading Gene Synthesis service provider in the world, Creative Biogene has extensive experience in synthesis & cloning of genes/genomic DNA from many species. We can synthesize and clone any DNA sequences, even complex, GC-rich, repeated, or long genes, into prokaryotic, eukaryotic or viral vectors. Creative Biogene has accomplished hundreds of thousands of...
ImaBiotech is a Contract Research Organization and provides innovative services to get better and faster drug candidate evaluations. With our new multimodal imaging platform and software called Multimaging, we deliver fast and more reliable evaluation of drug efficacy and toxicity.
Metagenomics is the study of metagenomes, genetic material recovered directly from environmental samples. The broad field was referred to as environmental genomics, ecogenomics or community genomics. Recent studies use \"shotgun\" Sanger sequencing or next generation sequencing (NGS) to get largely unbiased samples of all genes from all the members of the sampled communities...
Genosphere Biotechnologies may be a laboratory of extremely older organic chemists and biochemists dedicated to providing dependable and best research tools as well as fluorescent peptide synthesis etc.